The GSL Estrogen Pathway & DNA Adduct Biomarker Panel supports targeted LC-MS/MS analysis of estrogen hormones, estrogen metabolites, selected estrogen conjugates, and selected estrogen-derived DNA adduct biomarkers for research applications. This panel is designed for studies involving estrogen metabolism, oxidative metabolism, DNA damage biomarkers, toxicology, cancer-related research, and pathway-level biomarker analysis.
What This Panel Measures
Representative analyte classes may include:
- Parent estrogens
- Hydroxyestrogens
- Methoxyestrogens
- Ketoestrogens
- Estrogen sulfates and glucuronides
- Selected estrogen-derived DNA adduct biomarkers
- Selected estrogen-related conjugates and oxidative pathway biomarkers
Representative Analytes
Representative analytes may include estrone, estradiol, estriol, 2-hydroxyestrogens, 4-hydroxyestrogens, methoxyestrogens, ketoestrogens, 16α-hydroxyestrone, selected estrogen sulfates, selected estrogen glucuronides, and selected estrogen-derived DNA adduct biomarkers.
Sample Types
Urine, serum/plasma, tissue, cells, extracts, and other matrices may be supported depending on analyte class and project requirements.
Applications
- Estrogen metabolism research
- Cancer-related biomarker studies
- DNA adduct and oxidative damage research
- Toxicology and exposure biology
- Pathway-level estrogen biomarker profiling
- Custom estrogen metabolite/adduct studies
Important Note
Specialized estrogen-derived adducts, conjugates, and custom biomarker configurations may be available for qualified research projects. Full technical details and specialized analyte lists are not fully disclosed publicly.