The GSL Oxysterol & Sterol Metabolism Panel supports targeted LC-MS/MS analysis of cholesterol-related metabolites, oxysterols, sterol oxidation products, and sterol pathway biomarkers.
What This Panel Measures
Representative analyte classes may include:
- Cholesterol and cholesterol sulfate
- Hydroxycholesterols
- Ketocholesterols
- Epoxycholesterol metabolites
- Sterol intermediates
- Selected sterol oxidation products
Representative Analytes
Representative analytes may include cholesterol, cholesterol sulfate, 4β-hydroxycholesterol, 7α-hydroxycholesterol, 7β-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol, 20α-hydroxycholesterol, 22β-hydroxycholesterol, 7-ketocholesterol, epoxycholesterol metabolites, lathosterol, dehydrocholesterol-related metabolites, and selected sterol oxidation products.
Sample Types
Serum/plasma, tissue, cells, extracts, and other research matrices may be supported depending on project needs.
Applications
- Cholesterol metabolism
- Oxysterol biology
- Liver-gut axis research
- Neurodegeneration-related research
- Inflammation and sterol oxidation studies
- Preclinical and translational biomarker studies
What Clients Receive
Reports may include targeted oxysterol/sterol concentrations, matrix-specific values, QC-reviewed data tables, and optional interpretation.