Estrogen Pathway Profiling Kit

Description

The Estrogen Pathway Profiling Kit is a UPLC–MS/MS research service for measurement of parent estrogens, estrogen metabolites, and selected estrogen conjugates involved in estrogen biosynthesis and metabolism.

This panel includes 12 defined analytes covering major estrogens, sulfated estrogens, hydroxyestrogens, and methoxyestrogens. It supports studies involving estrogen metabolism, endocrine pathway research, oxidative estrogen metabolism, methylation, sulfation, chemical carcinogenesis, preclinical models, and industrial research applications.

Each order includes analysis of 10 research samples. Sample matrices may include urine, serum/plasma, saliva, tissue, cells, extracts, and other biological or research matrices, depending on analyte class, expected concentration range, extraction method, and project scope.

GSL’s LC-MS/MS workflow is designed to provide sensitive, selective, and QC-reviewed estrogen pathway measurements with research-ready data reporting. Selected estrogen-derived DNA adduct biomarkers, expanded estrogen panels, and customized pathway configurations may be available upon request.

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Target Analytes

• Estrone (E1)
• Estradiol (E2)
• Estriol (E3)
• Estrone sulfate (E1-SO4)
• Estradiol sulfate (E2-SO4)
• 2-Hydroxyestrone
• 4-Hydroxyestrone
• 16α-Hydroxyestrone
• 2-Methoxyestrone
• 2-Methoxyestradiol
• 4-Methoxyestrone
• 4-Methoxyestradiol

Additional analytes, estrogen conjugates, estrogen-derived adduct biomarkers, and customized panel configurations may be available upon request.

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Key Features

• Comprehensive targeted profiling of parent estrogens, estrogen metabolites, and selected estrogen conjugates

• Measures 12 defined standard analytes relevant to estrogen biosynthesis, estrogen metabolism, sulfation, oxidative estrogen metabolism, methylation, and endocrine pathway research

• Advanced UPLC–MS/MS analysis for sensitive, selective, and specific estrogen-pathway measurement

• Supports applicable research matrices such as urine, serum/plasma, saliva, tissue, cells, extracts, and other biological or research matrices, depending on analyte class, expected concentration range, and project scope

• Intended for scientific research, estrogen metabolism studies, endocrine pathway research, reproductive biology, toxicology, chemical carcinogenesis, preclinical research, pharmaceutical research, product-development, and industrial applications

• Clear sample submission instructions for research sample handling and shipment

• Includes analysis of 10 research samples per order

• Listed analytes represent the standard panel; custom estrogen metabolites, estrogen conjugates, estrogen-derived adduct biomarkers, modified panels, expanded estrogen pathway configurations, or project-specific configurations may be available depending on research objectives, sample matrix, expected concentration range, and method feasibility

Price includes analysis of 10 research samples.

For larger studies, institutional PO billing, bundled projects, or custom panel requests, please Request a Quote.