Description
The Folic Acid One-Carbon Metabolism Profiling Kit is a UPLC–MS/MS research service for measurement of selected metabolites involved in folate metabolism, one-carbon transfer, methylation balance, choline/betaine metabolism, transsulfuration, and related biochemical pathways.
This panel includes 18 defined analytes and supports research involving folate-dependent metabolism, methylation biology, nutritional biochemistry, metabolic pathway studies, preclinical research, and product-development applications.
Each order includes analysis of 10 research samples. Sample matrices may include urine, serum/plasma, tissue, cells, extracts, and other biological or research matrices, depending on analyte stability, expected concentration range, extraction method, and project scope.
GSL’s LC-MS/MS workflow is designed to provide selective, QC-reviewed one-carbon pathway measurements with research-ready data reporting. Additional folate, methylation, transsulfuration, and B-vitamin-related biomarkers may be available upon request.
Target Analytes
- Folic acid
- Tetrahydrofolate
- 5-Methyl-THF / 5-MTHF
- 5,10-Methylene-THF
- 5,10-Methenyl-THF
- 10-Formyl-THF
- Pteroyltri-γ-glutamic acid / PteGlu3
- Betaine
- Choline
- Cystathionine
- Glycine
- Homocysteine
- Methionine
- Sarcosine / N-methylglycine
- Taurine
- Dimethylglycine / DMG
- SAM
- SAH
Additional analytes and customized panel configurations may be available upon request.
Key Features
- Measurement of selected metabolites in folate, one-carbon, methylation, choline/betaine, and transsulfuration pathways
- 18 defined analytes
- Advanced UPLC–MS/MS analysis
- Includes analysis of 10 research samples per order
- Supports urine, serum/plasma, tissue, cells, extracts, and other applicable research matrices
- Suitable for nutrition, methylation biology, metabolic pathway, preclinical, research, and industrial applications
- Additional one-carbon, folate, methylation, and B-vitamin-related biomarkers available upon request




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